En coordination avec le cours de Biostatistiques I (11M004), les séances de Biostatistiques I : Applications (11M904) et Répétitoire (11B800) proposent une application à la biologie des concepts-clé en probabilités et statistiques. Les séances hebdomadaires seront dédiées à contextualiser l'utilité et l'utilisation de ces concepts pour aborder des connaissances dans le domaine des sciences du vivant. Ceci s'effectuera à travers la résolution, par les étudiants-es, de problèmes présentés sous forme d'exercices sur des exemples tirés exclusivement du domaine des sciences du vivant. Des corrections interactives (entre enseignants-es et étudiants-es) seront proposées. Le recours à l'utilisation du logiciel R est inclus dans les séances.

Illustrer des aspects théoriques abordés lors du cours de Biologie Fondamentale II - Introduction à la Microbiologie.

  1. Apprendre à ensemencer des cultures bactériennes et travailler stérilement;
  2. Apprécier l'effet de facteurs de l'environnement sur la croissance bactérienne;
  3. Observer et documenter la croissance microbienne;
  4. Rendre des cellules compétentes pour la transformation;
  5. Transformer des cellules bactériennes avec de l'ADN plasmique;
  6. Transférer un plasmide d'une bactérie à l'autre par conjugaison;
  7. Sélectionner et dénombrer les bactéries transformées;
  8. Observer l'effet de bactéries du sol sur la croissance des plantes;
  9. Biotechnologie: utilité d'un gène reporter pour suivre un processus infectieux.
  10. Coloration de Gram: distinguer les bactéries gram positif de celles gram négatif;

Introduire des notions de microbiologie aux étudiants en 1ère année du Bachelor en Biologie.
Les notions fondamentales qui seront abordées permettront de:

  1. distinguer les structures des cellules bactériennes de cells des cellules eucaryotes;
  2. identifier les difficultés inhérentes à l'étude des populations microbiennes;
  3. connaître les principaux facteurs qui influencent le développement de microorganismes;
  4. décrire les moyens utilisés pour contrôler le développement des microorganismes;
  5. distinguer les mécanismes génétiques bactériens de ceux des cellules eucaryotes.

This training course provides students with basic knowledge in population genetics through computer-assisted analyses of different molecular datasets provided by the teachers. The practical work consists in carrying out the different steps of a study aiming at defining the genetic structure of populations: data management, data analysis using usual computer programs in population genetics, interpretation of the results. The theoretical concepts are introduced at the beginning of each course and trained during the practical sessions. Several scientific conferences are also given by invited speakers. This training course is for students following the master in biology but also for PhD students (it is part of the doctoral program in Ecology and Evolution of the CUSO - https://biologie.cuso.ch/ecologie-et-evolution/welcome/)

La pratique des statistiques dans l'environnement R

-- Les cours commencent le mercredi 20 septembre 2017

Master's course on applied statistics and probability for bio*

-- The course starts Monday 25 September 2017, at 14:15 in room Sciences III - 1S081

This course intends to present useful computer tools and techniques for young researchers in biology that substantially extend basic computer knowledge acquired at undergraduate levels. The course concentrates on GNU/Linux environment and tools because it is powerful, free and easy to install in any kind of computer. Moreover, most of the computer clusters available for scientists run Linux.
The course is intended for beginners and for more advanced people, its level of complexity increasing through the four days. Basic knowledge in computing and programming is a plus but is not mandatory. The first part of the course will consist in learning the basic of GNU/Linux: installation of the environment, useful shell commands to work with text files, simple command lines and the use of regular expressions, pipes, and short scripts. The second part will consist in developing more complex scripts, as well as exercises using a computer cluster.
The training will provide a minimal theoretical basis in each of the topics listed below and concentrate on practical aspects through numerous applications. It will confer a working autonomy to solve problems while handling data and conducting data analyses pertinent to the researcher in biology.

Poster

The objectives of the course are to acquire theoretical and practical knowledge of the major techniques relevant for structural biology and biological mass spectrometry. For structural biology the concepts and applications of three major techniques will be presented including: electron microscopy, X-rays, and nuclear magnetic resonance (NMR). In the mass spectrometry part the principal techniques will be presented as well as its application to Systems Biology.

This course is designed for Master students in Biology and Biochemistry as well as for PhD students from the Doctoral School in Pharmaceutical Sciences. The class will only be held with a minimum of 8 students. The course material will be available on moodle .

After a general introduction in structural biology with an overview of the major techniques the course will be organized around four modules: electron microscopy, NMR, X-Ray and mass spectrometry. Each module will present the basic principles and the mainstream applications.

After a general introduction in structural biology with an overview of the major techniques the course will be organized around four modules: electron microscopy, NMR, X-Ray and mass spectrometry. Each module will present the basic principles and the mainstream applications.

Teachers: M.: G. HOPFGARTNER (po), T. SCHALCH (past), L. SCAPOZZA (po), F. BARJA (cc), O. SCHAAD (cc), E. VARESIO (mer)., Mrs. C. BESNARD (mer), E. RIVARA-MINTEN (ce), S. MICHALET (cols).

Responsables: